03 Oquendo.indd

Address correspondence to: Ilia Oquendo-Jiménez, PhD, School of PharmacyMedical Sciences Campus, University of Puerto Rico, P.O. Box 365067, San Juan, PR 00936-5067. Tel: (787) 758-2525 Ext. 5437 • Fax (787) 767-2796 • Email: ilia. [email protected] Background: Alzheimer’s disease (AD) is the most common form of dementia worldwide. In Hispanic populations there are few validated tests for the accurate identification and diagnosis of AD. The Clinical Dementia Rating (CDR) scale is an internationally recognized questionnaire used to stage dementia. This study’s objective was to develop a linguistic adaptation of the CDR for the Puerto Rican population. Methods: The linguistic adaptation consisted of the evaluation of each CDR question (item) and the questionnaire’s instructions, for similarities in meaning (semantic equivalence), relevance of content (content equivalence), and appropriateness of the questionnaire’s format and measuring technique (technical equivalence). A focus group methodology was used to assess cultural relevance, clarity, and suitability of the measuring technique in the Argentinean version of the CDR for use in a Puerto Rican population. Results: A total of 27 semantic equivalence changes were recommended in four categories: higher than 6th grade level of reading, meaning, common use, and word preference. Four content equivalence changes were identified, all focused on improving the applicability of the test questions to the general population’s concept of street addresses and common dietary choices. There were no recommendations for changes in the assessment of technical equivalence. Conclusions: We developed a linguistically adapted CDR instrument for the Puerto Rican population, preserving the semantic, content, and technical equivalences of the original version. Further studies are needed to validate the usefulness of the adapted CDR instrument with the staging of Alzheimer’s disease in the Puerto Rican population. [P R Health Sci J 2010;2:102-108]